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From Wikipedia, the free encyclopedia. Alpha hydroxy acids Cosmetics chemicals. This article needs additional citations for verification. Improvement of photodamaged skin with alpha-hydroxy acid AHA: Glycolic acidhaving the smallest molecular size, is the Hidroxixcidos with greatest bioavailability and penetrates the skin most easily; this largely accounts for the popularity of this product in cosmetic applications.
Alpha hydroxy acid
Chemical peels tend to have more severe side-effects including blistering, burning and skin discoloration, although they are usually mild and go away a day or two after treatment. AHAs are a group of organic carboxylic compounds. Principles of organic synthesis. This page was last edited on 24 Decemberat Understanding skin structure and cutaneous aging is helpful to a discussion of the topical action of AHAs.
They are often found in products that aid in the reduction of wrinkles as well as to soften strong, defining lines and improve the overall look and feel of the skin.
Alpha hydroxy acid – Wikipedia
AHAs are well known for their use in the cosmetics industry. Retrieved from ” https: Bioavailability influenced primarily by small molecular size is an important factor in a compound’s ability to penetrate the top layer of the skin.
AHAs with greater bioavailability appear to have deeper dermal effects.
Views Read Edit View history. Please help improve this article by adding citations to reliable sources. European Academy of Dermatology and Venereology. In other projects Wikimedia Commons. The benefit of such short-contact application chemical peels depends on the pH of the solution the more acidic the product, or the lower the pH, the more pronounced the resultsthe concentration of GA higher concentrations produce more vigorous responsethe length of application and prior skin conditioning such as prior use of topical vitamin A products.
It is important to understand that glycolic acid peels are chemical peels with similar risks and side effects as other peels. A clinical, histological, and ultra-structural study. AHAs most commonly used in cosmetic applications are typically derived from food products including glycolic bdta from sugar canelactic acid from sour milkmalic acid from applescitric acid from citrus fruits and tartaric acid from grape wine.
Rapid Communications in Mass Spectrometry. Some of the side effects of AHAs chemical peeling can include hyper-pigmentation, persistent hidroxaicidos, scarring, as well as flare up of facial herpes infections “cold sores”.
For any topical compound to be effective, including AHA, brta must beat into the skin where it can act on living cells. They may be either naturally occurring or synthetic. Ullmann’s Encyclopedia of Industrial Chemistry.
Unsourced material may be challenged and removed. AHAs are generally safe when used on the skin as a cosmetic veta using the recommended dosage. Glycolic acid, lactic acid, and citric acid, on topical application to photodamaged skin, have been shown to produce increased amounts of mucopolysaccharides and collagen and increased skin thickness without detectable inflammation, as monitored by skin biopsies.
The FDA has also warned consumers that care should be taken when using AHAs after an industry-sponsored study found that they can increase photosensitivity to the sun. James; Bada, Hidroxiacivos L. Although these compounds are related to the ordinary carboxylic acidsand therefore are weak acids, their chemical structure allows for the formation of an internal hydrogen bond between the hydrogen at the hydroxyl group hidroxiacidox one of the oxygen atoms of the carboxylic group.
Newer formulations combine glycolic acid with an amino acid such as arginine and time-release formulations that reduces the risk of irritation without affecting glycolic acid efficacy.
June Learn how and when to remove this template message. Articles needing additional references from June All articles needing additional references All articles with unsourced statements Articles with unsourced statements from August Moy; Debra Luftman; Lenore S. James Morriss3rd. Hisroxiacidos aging, while having epidermal concomitants, seems to involve primarily the dermis and nidroxiacidos caused by intrinsic and extrinsic aging factors. It appears that AHAs modulate this formation through diminished cellular cohesion between corneocytes at the lowest levels of the stratum corneum.
Human skin has two principal components, the avascular epidermis and the underlying vascular dermis.